Pythia provides deep learning-driven precision in CRISPR–Cas9 genome engineering

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Research Briefing Published: 01 September 2025 Nature Biotechnology (2025)Cite this article Subjects Precision CRISPR–Cas9-mediated genome engineering remains challenging, particularly gene integration and editing in non-dividing cells. We present Pythia, a deep learning solution that forecasts optimal repair templates and enables predictable and accurate genome editing in diverse cellular contexts, bothContinue Reading