Secukinumab Cuts Chronic Pain in Hidradenitis Suppurativa

TOPLINE: Compared with placebo, secukinumab demonstrated superior pain reduction in moderate to severe hidradenitis suppurativa in two phase 3 trials. Improvements in pain were sustained through week 52 and were associated with better quality of life outcomes. METHODOLOGY: Researchers analysed 1084 patients with moderate to severe hidradenitis suppurativa from twoContinue Reading

Ph-Positive Leukemia: No Longer a Death Sentence?

TOPLINE: A combination of targeted treatment and immunotherapy has revolutionized Philadelphia chromosome–positive acute lymphoblastic leukemia management, achieving long-term survival rates of 75%-80% without systemic chemotherapy or transplantation. METHODOLOGY:  Researchers initiated a treatment protocol in 2000 using tyrosine kinase inhibitors plus glucocorticoids for induction without systemic chemotherapy. Analysis included first-, second-,Continue Reading