Stem Cell-Derived Islets Still Producing Insulin at 1 Year

CHICAGO — Ten people with type 1 diabetes, who had recurrent severe hypoglycemia and hypoglycemic unawareness, have remained insulin-independent for over a year following allogeneic stem cell-derived islet-cell therapy with immunosuppression, according to new phase 1/2 data from the multicenter FORWARD study sponsored by Vertex Pharmaceuticals. The insulin-producing therapy VX-880,Continue Reading

DIF Microscopy Helps Diagnose Pediatric Skin Diseases

TOPLINE: Direct immunofluorescence (DIF) microscopy showed a 15.5% positivity rate in pediatric patients and changed the clinical diagnosis in 16.7% of those cases. METHODOLOGY: Researchers conducted a retrospective review of DIF data from 986 patients aged 0-18 years (mean age, 12 years) at the Mayo Clinic’s reference immunodermatology laboratory betweenContinue Reading