PSMA-PET Challenges Current Prostate Cancer Staging

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TOPLINE:  Prostate-specific membrane antigen–positron emission tomography (PSMA-PET) detected metastatic disease in 46% of patients with high-risk prostate cancer previously classified as nonmetastatic by conventional imaging. Results were positive in 84% of patients, with polymetastatic disease found in 24% of cases. METHODOLOGY: Recurrent nonmetastatic hormone-sensitive prostate cancer is characterized by increasingContinue Reading

Preoperative Radiosurgery for Brain Metastases Shows Promise

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TOPLINE: Patients undergoing stereotactic radiosurgery before resection of brain metastases demonstrated low rates of local recurrence, radionecrosis, and nodular leptomeningeal disease at 12 and 24 months, a new analysis found. METHODOLOGY: For patients undergoing resection for brain metastases, postoperative stereotactic radiosurgery improves local control. However, radiosurgery after surgery comes withContinue Reading

IBS Relief: Is Combining Low-FODMAP/Gluten-Free the Answer?

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For adults with irritable bowel syndrome (IBS), combining a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) and a gluten-free diet (GFD) appears to improve clinical symptoms and reduce anxiety and depression, according to a new systematic review and meta-analysis. Across several studies, the combined diet improved qualityContinue Reading