Iron Overload: The Silent Bone Breaker

TOPLINE: Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload. METHODOLOGY: Iron overload’s association with decreased bone mineral density is established, but its relationship to osteoporotic fractureContinue Reading

Adding temozolomide to radiation therapy improves survival in adult patients with slow-growing brain tumor, trial finds

Credit: Anna Shvets from Pexels Both radiation and temozolomide, a generic chemotherapy treatment in pill form, have meaningful single-modality anti-tumor activity against slow-growing, low-grade gliomas. The randomized phase 3 trial E3F05 by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) tested whether combined therapy using temozolomide alongside radiation therapy is more effectiveContinue Reading