Meta-analysis Probes Rare Potential Vision Risk of GLP-1s

TOPLINE: Patients treated with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) appear to have a very low incidence of nonarteritic anterior ischemic optic neuropathy (NAION) when appropriately prescribed for obesity or diabetes.  METHODOLOGY: A retrospective observational study recently suggested that semaglutide treatment may be associated with more than a fourfoldContinue Reading

Iron Overload: The Silent Bone Breaker

TOPLINE: Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload. METHODOLOGY: Iron overload’s association with decreased bone mineral density is established, but its relationship to osteoporotic fractureContinue Reading