DC plane crash raises questions about strained resources, military use of air spaces

Wednesday’s midair collision of a civilian airliner and military helicopter at Reagan National Airport left no survivors and called into question whether the airport’s strained resources can handle all the demands put on it. There’s no question that airline safety has steadily improved worldwide. But in places, rising air traffic,Continue Reading

AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion

Main Adeno-associated virus (AAV) vectors proved to be effective and safe for hepatocyte-targeted reversal of factor IX and VIII deficiency in hemophilia B and A, respectively, with the AAV5 capsid being the first to receive Food and Drug Administration (FDA) approval1,2. However, these achievements of therapeutic efficacy cannot be readilyContinue Reading

A human metabolic map of pharmacological perturbations reveals drug modes of action

Data availability All data generated or analyzed during this study are included in this article as Supplementary Data. Metabolome data and results from data analysis can be found as Supplementary Datasets or at https://www.ebi.ac.uk/biostudies/studies/S-BSST1724 and https://git.scicore.unibas.ch/zampieri-lab/humanmetabolicmap and interactively browsed at https://zampierigroup.shinyapps.io/HumanMetabolicMap. All data needed to reproduce and rerun statistical tests,Continue Reading

How to spend the perfect day in Granada, Spain

This article was adapted from National Geographic Traveller (UK). Granada’s hill caves, labyrinthine alleyways and the medieval Moorish quarter combine to make it an enigmatic city break destination. This provincial capital in southern Spain offers literary lunches, mirador sunsets and Islamic architecture, with the spirit of flamenco infusing every facetContinue Reading