Site-specific drug release of monomethyl fumarate to treat oxidative stress disorders

Main The transcription factor nuclear factor E2-related factor 2 (NRF2) is an attractive therapeutic target because its activation stimulates a panoply of antioxidants that naturally resolve oxidative stress, a process central to diseases with great societal burden1,2,3,4. However, systemically distributed activators such as monomethyl fumarate (MMF) have global on-target actionsContinue Reading

PM Hotel Group and Sightline Hospitality Announce Strategic Merger

CHEVY CHASE, Maryland—PM Hotel Group and Sightline Hospitality announced a strategic merger. This partnership marks a development in PM Hotel Group’s growth trajectory, specifically within PM Hotel Group’s lifestyle hotel division Modus by PM Hotel Group, complementing the organization’s verticals of lifestyle, differentiated hospitality, and experiential travel. The merger expandsContinue Reading

Kecia Lewis Requests Apology From Patti LuPone For “Bullying” And “Racially Microaggressive” Comments Calling ‘Hell’s Kitchen’ “Too Loud”

Kecia Lewis requested an apology from Broadway icon Patti LuPone for saying the production Hell’s Kitchen was “too loud” — a remark the Tony-winning performer characterized as “bullying” and “racially microaggressive.” In a five-minute-long video open letter, Lewis — who won a Tony this year for her performance in theContinue Reading

It Girl Codes (November 2024)

Looking for extra diamonds or new cosmetics in It Girl? This page has compiled every redeemable code currently available in It Girl, so you can instantly get your hands on both in the Roblox fashion game. Active It Girl Codes (November 2024) Below, you’ll find a list of every activeContinue Reading