TOPLINE: Higher variability in the levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, or triglycerides was independently associated with an increased risk for heart failure in patients with type 2 diabetes (T2D). METHODOLOGY: The relationship between variability in lipid fractions and the risk for heart failureContinue Reading
Medbrief Immune-Related Adverse Events Associated With Better Survival Outcomes in Extensive-Stage Small Cell Lung Cancer TOPLINE: Immune-related adverse events (irAEs) were associated with significantly improved progression-free survival (PFS) and overall survival (OS) in patients with extensive-stage small cell lung cancer (SCLC) who received chemoimmunotherapy compared with that in those whoContinue Reading
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Credit: Pixabay/CC0 Public Domain Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren’t completely sure why. They may have a better idea now, however, thanks to a study in GeroScience. “Immune cell changes occur duringContinue Reading
TOPLINE: A recent study identified three clinically distinct vitiligo profiles on the basis of Vitiligo Patient Priority Outcomes (ViPPO) responses from real-world patient data. Classes with more severe emotional and social functioning impacts had more severe disease per physician assessment, visible areas of lesion involvement, and work productivity and quality-of-lifeContinue Reading
WASHINGTON, DC — Research on the gut microbiome — and clinical attention to it — has focused mainly on bacteria, but bacteriophages and fungi play critical roles as well, with significant influences on health and disease, experts said at the Gut Microbiota for Health (GMFH) World Summit 2025. Fungi accountContinue Reading
Evidence continues to accrue that prenatal exposure to some synthetic chemicals in the environment is associated with adverse pregnancy outcomes and negative effects on the neonatal metabolome and neurobehavior scores. Although ubiquitous compounds such as phthalates and phenols affect several aspects of general human and reproductive health, preventing or reducingContinue Reading
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